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Chin filler retreatment safety under study

NCT ID NCT07566286

Symptom relief Sponsor: Galderma R&D Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 4 times

Summary

This study looks at the safety of using Restylane Lyft with Lidocaine, a hyaluronic acid gel, for a second treatment to improve the chin profile. About 100 adults aged 22 and older will receive the retreatment. The main goal is to track any side effects related to the gel or injection procedure three months after retreatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Restylane Lyft with Lidocaine (hyaluronic acid gel)
What this could lead to
If successful, this could confirm that retreating the chin with Restylane Lyft is safe for improving chin shape.
What could go wrong
This is a small, early-stage safety study with no comparison group, so results may not apply to everyone. Risks include allergic reactions or injection-site issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Feb 2028

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

22 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Males or non-pregnant, non-breastfeeding females, 22 years of age or older. 2. Intent to receive treatment for augmentation and correction of retrusion in the chin region. Exclusion Criteria: 1. Known/previous allergy or hypersensitivity to any injectable hyaluronic acid (HA) gel or to gram positive bacterial proteins. 2. Known/previous allergy or hypersensitivity to local anesthetics, e.g. lidocaine or other amide-type anesthetics. 3. Previous or present multiple allergies or severe allergies, such as manifested by anaphylaxis or angioedema, or family history of these conditions. 4. Previous facial surgery (including facial aesthetic surgery and liposuction), below the level of the horizontal line from subnasale. 5. Any previous aesthetic procedures or implants. 6. Presence of any disease or lesions near or on the area to be treated.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chin augmentation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    8 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Galderma Investigational Site # 7030

    RECRUITING

    Coral Gables, Florida, 33134, United States

  • Galderma Investigational Site # 7042

    RECRUITING

    Atlanta, Georgia, 30331, United States

  • Galderma Investigational Site # 7043

    NOT_YET_RECRUITING

    Bethesda, Maryland, 20852, United States

  • Galderma Investigational Site # 7118

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Galderma Investigational Site # 8662

    RECRUITING

    Spring, Texas, 77388, United States

  • Galderma Investigational Site # 8680

    RECRUITING

    Westport, Connecticut, 06880, United States

  • Galderma Investigational Site # 8682

    RECRUITING

    Coral Gables, Florida, 33134, United States

  • Galderma Investigational Site # 8774

    RECRUITING

    Boynton Beach, Florida, 33437, United States

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