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Breathe better, think faster? new study tests the link
NCT ID NCT07637331
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether training your breathing muscles for 8 weeks can improve your thinking skills when you have to breathe against resistance. Researchers will measure diaphragm thickness and cognitive performance in 32 healthy adults aged 18-40. The goal is to see if stronger breathing muscles help the brain work better during hard breathing.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- inspiratory muscle training device
- What this could lead to
- If it works, this could point toward a simple way to help people think more clearly when they are short of breath.
- What could go wrong
- This is a small, early study in healthy young adults, so results may not apply to people with breathing or thinking problems. The sham group may also show some benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 32 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18-40 years old * Body mass index \<30 kg/m2 * Naïve to IMT * \>75% of predicted forced expiratory volume in 1 second (FEV1) / forced vital capacity (FVC) (FEV1/FVC) * Access to smart phone or tablet with internet Exclusion Criteria: * Diagnosed: * Cardiovascular disease * Respiratory disease (including asthma) * Metabolic disease * Currently pregnant * Unable to adhere to the IMT protocol * Answering 'yes' to any of the questions on page one of the PAR-Q+ * Abnormal cognition assessed via the Montreal Cognitive Assessment (score of 25 or less) * Self-reported color blindness * Significant acute or chronic medical, neurologic, or illness in the participant that, in the judgment of the Principal Investigator, could compromise subject safety, limit the ability of the participant to complete the study, and/or compromise the objectives of the study
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Indiana University
RECRUITINGBloomington, Indiana, 47405, United States
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