New tooth treatment could brighten Kids' smiles and ease pain
NCT ID NCT07469124
First seen Jun 27, 2026 · Last updated Sep 01, 2026 · Updated 2 times
Summary
This study looks at whether a tooth-colored resin treatment, with or without mild enamel abrasion, can improve the appearance and reduce sensitivity of front teeth in children aged 6-14 with molar incisor hypomineralization (MIH). Fifty-five children will receive the treatment and be followed for 12 months. The goal is to see if this minimally invasive approach improves their quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Resin infiltration (a tooth-colored resin applied to enamel lesions)
- What this could lead to
- If successful, this could provide a minimally invasive way to improve the look and sensitivity of affected teeth in children, potentially boosting their quality of life.
- What could go wrong
- This is a small, early-stage study with only 55 participants and no control group, so results may not apply broadly. The treatment may not fully resolve symptoms or last long-term.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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55 people
The number who actually took part.
- Started
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Dec 2025
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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6 to 14 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The child must be between 6 and 14 years old, * Diagnosed with molar incisor hypomineralization (according to EAPD criteria) and have lesions in the incisors, * The tooth to be treated must not be cavitated or must not require restoration, * Having the reading and writing skills to answer the scale, * Having no communication impairments (auditory, visual, cognitive), * Having no systemic illnesses that would affect oral health, * Not taking any medications that would affect oral health, * Both the child and their parents must be willing to complete the scale, * Agree to attend the 12-month follow-up appointments. Exclusion Criteria: * Presence of enamel defects other than MIH in the target tooth, such as dental fluorosis, amelogenesis imperfecta, or enamel hypoplasia; * Presence of significant caries, extensive dentin caries, large restorations, fissure sealants, composite restorations, or any existing restoration that may interfere with lesion evaluation in the affected tooth; * Presence of spontaneous pain, abscess/fistula, suspected pulpitis, or need for endodontic treatment in the affected tooth; * Presence of orthodontic appliances (e.g., brackets or bands) on the tooth to be evaluated that may interfere with color measurement; * Known allergy or hypersensitivity to the dental materials used in the study; * History of recent microabrasion, bleaching, resin infiltration, or similar procedures performed on the affected tooth; * Inability of the participant to read and write sufficiently to complete the questionnaire; * Presence of any systemic disease that may affect oral health; * Use of medications that may affect oral health; * Presence of any communication barriers (hearing, visual, or cognitive impairment) that may interfere with study participation; * Refusal or unwillingness of either the participant or the parent/guardian to complete the questionnaire.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
İnönü University Faculty of Dentistry
Malatya, Battalgazi, 44320, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Battle of the bright smiles: which technique best hides MIH white spots?
- Could bleaching before mousse fix Kids' chalky teeth?