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Can a virtual blood pressure clinic keep your brain sharp?

NCT ID NCT05138601

Disease control Sponsor: University of Kansas Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests a virtual clinic where pharmacists monitor blood pressure, adjust medications, and provide telehealth support to older adults (65+) with high blood pressure. The goal is to see if better blood pressure control can also help prevent cognitive decline. About 1,000 participants will use home monitors and a smartphone app to track their numbers over 24 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
virtual collaborative care clinic (home blood pressure monitoring, telehealth, medication management by pharmacists)
What this could lead to
If successful, this could offer an effective way to manage high blood pressure remotely, potentially reducing the risk of cognitive decline in older adults.
What could go wrong
This is a phase II pragmatic trial, so results are still preliminary. The approach may not work for everyone, and long-term benefits for cognition are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

1,000 people

The number who actually took part.

Started

Nov 2021

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 65 and older * Active patient in participating primary care clinic * Access to compatible "smartphone" or device (i.e., Android, Kindle or Apple with internet connectivity or mobile network) * Elevated BP as defined by * SBP \>140 at current visit AND documented history of hypertension OR SBP \> 140 at current visit and at another visit in last 18 months OR SBP \>160 at current visit * Sufficiently fluent in English to participate in study procedures * Adequate hearing to complete study procedures * Able to give their own signed consent * Health insurance coverage by Medicare Exclusion Criteria: * Clinically significant illness that may affect safety or completion per their treating PCP or study physician * Needing interpreter for clinic visits (through Electronic Health Record) * Currently in hospice care * Currently receiving chemotherapy * Unable to take accurate BP measurement, either due to inability to follow protocol to check BP or due to medical conditions such as lymphedema or dialysis access on both arms. * Currently participating in another intervention trial * End stage kidney disease on dialysis * Diagnosis of dementia (i.e., dementia, Alzheimer's disease, vascular dementia, dementia with Lewy bodies, frontotemporal dementia) * Chronic active disease with expected life expectancy \< 2 years as determined by the study team

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Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypertension

Contacts and locations

Locations

  • University of Kansas Health System

    Kansas City, Kansas, 66160, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

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