Anesthesia side effect solution? remifentanil tested for itch and tingle
NCT ID NCT07092384
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether adding remifentanil can reduce itching and tingling caused by fospropofol, a common anesthesia drug. 265 adults having non-cardiac surgery took part. Researchers checked for these side effects right after the drug was given and tracked how long they lasted.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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265 people
The number who actually took part.
- Started
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Jul 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18-80 years old, plans to undergo elective non-cardiac surgery under general anesthesia. * ASA I-II; * The operation duration \> 30 min; * BMI 18-30kg /m2; * Sign the informed consent form. Exclusion Criteria: * history of drug abuse or alcohol dependence; * used sedative or analgesic drugs before operation; * with severe liver and kidney function impairment; * allergic to propofol and lipids; * surgery that directly affect hemodynamics with surgical operations, such as macrovascular surgery; * abnormal coagulation function, endocrine diseases or other effects on hemodynamic status; * Participation in other clinical researchers in the past 3 months
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tongji Hospital
Wuhan, Hubei, 430030, China
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