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Exercise before surgery: could ReHIIT boost recovery for bowel cancer patients?

NCT ID NCT07313332

Knowledge-focused Sponsor: University of Nottingham Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This pilot study will test a combined exercise program called ReHIIT (resistance training plus high-intensity interval cycling) in 14 healthy adults. The goal is to see how the body responds to this type of exercise, so researchers can later compare it to colorectal cancer patients. The study does not involve any drugs or treatments for cancer itself.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ReHIIT training (resistance exercise plus high-intensity interval cycling)
What this could lead to
If successful, this could help design better exercise programs to prepare colorectal cancer patients for surgery and improve recovery.
What could go wrong
This is a very small pilot study in healthy volunteers, not cancer patients. Results may not translate to actual patients or lead to any treatment changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 14 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant is willing and able to give informed consent for participation in the study. * Availability and willingness to attend the Royal Derby Hospital site for a minimum of 8 exercise sessions and 2 assessment sessions across the study period. Exclusion Criteria: * BMI \<18 or \>35 kg/m2 * Known active cance * Known metabolic disease * Current known neurological or musculoskeletal conditions (e.g. epilepsy) * Active known cardiovascular, cerebrovascular or respiratory disease - e.g: * Uncontrolled hypertension (systolic BP \> 160 mmHg or diastolic BP \>100 mmhg) * Myocardial infarction within the last 6 months or unstable angina * Heart failure (New York Heart association Class III/IV) * Arrhythmia * Right to left cardiac shunt * Aneurysm of a named blood vessel * COPD * Pulmonary hypertension * Exercise-induced or brittle asthma * Previous stroke/transient ischaemic attack * Abnormal ECG results (at the discrepancy of the study doctor) * Patients who are unable to undergo CPET based on ATS/ACSS guidelines \^ * Pre-existing clotting disorder known to the participant or anticoagulant use * Family history of severe bleeding requiring medical intervention * Participation in a research study in the last 3 months involving invasive procedures or an inconvenience allowance (ALL UoN FMHS UREC approved studies) * Pregnant or breastfeeding

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy adult male and female volunteers Intervention

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Medical School, University of Nottingham, Royal Derby Hospital

    RECRUITING

    Derby, Derbyshire, DE223DT, United Kingdom

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