Can a 10-Week group program help clear Post-COVID brain fog?
NCT ID NCT07821385
First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time
Summary
Many people who had COVID-19 continue to struggle with fatigue, memory problems, and difficulty managing daily tasks. This study follows 120 adults with these symptoms who join a 10-week group rehabilitation program at a Swedish hospital. The program brings together occupational therapists, psychologists, physiotherapists, physicians, and social workers to offer education, discussion, and physical activity. Researchers want to learn which activities patients most want to improve and whether the program changes how they rate their daily performance, health, and life satisfaction.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a 10-week interprofessional group rehabilitation program combining cognitive training, education, and physical activity
- What this could lead to
- If the program helps, it could give clinics a clearer model for treating post-COVID brain fog and fatigue, and help patients return to work and daily activities.
- What could go wrong
- This is a small observational study at one Swedish clinic, so results may not apply to other patients or settings. The program may not improve symptoms for everyone, and the study cannot prove cause and effect.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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120 people
The number who actually took part.
- Started
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Aug 2021
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients aged 18-65 with persistent cognitive symptoms and fatigue following confirmed or strongly suspected COVID-19 infection, who have undergone assessment at the Cognitive Post-COVID Clinic at Danderyd Hospital and subsequently completed a team evaluation prior to participation in interdisciplinary rehabilitation. During the assessment, it is determined whether the patient needs and can benefit from rehabilitation.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Individuals aged 18 and older with confirmed COVID-19 or with a very likely prior COVID-19 infection. * Newly developed cognitive impairments or cognitive fatigue. --A clear temporal link between COVID-19 onset and symptom onset, with symptoms affecting return to previous activities/occupation. * The acute phase of illness ended at least 3 months earlier. * Basic investigations for specific differential diagnoses must have been completed at the initial clinic visit, according to "COVID-19 - persistent symptoms" (see viss.nu), excluding anemia, thyroid dysfunction, and alcohol overconsumption. Assessment for depression. * Medication review and relevant adjustments carried out with regard to the patient's symptoms Exclusion Criteria: * Predominant recurrent and/or fluctuating infectious symptoms, circulatory, respiratory, or cardiac problems. * Other symptoms due to organ failure that should primarily be managed by an organ specialist. * Severe psychiatric illness, including depression with pronounced cognitive symptoms. * Cognitive impairments primarily related to neurodegenerative disease or substance misuse, e.g., alcohol-related dementia, Korsakoff's dementia, or other dementia disorders.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Rehabilitaiton Medicine Stockholm
Stockholm, 18288, Sweden
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Other studies related to the condition(s) this trial covers.
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