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New combo tackles tough colorectal cancer in small trial

NCT ID NCT03828799

First seen Feb 28, 2026 · Last updated May 24, 2026 · Updated 15 times

Summary

This early-phase study tested a combination of two treatments—regorafenib and FOLFIRINOX chemotherapy—in 13 people with advanced colorectal cancer that has a specific gene change (RAS mutation). The main goal was to see if the combination is safe and tolerable. Researchers also looked at how long the cancer stayed under control. This is not a cure, but a way to manage the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre Antoine Lacassagne

    Nice, Alpes-Maritimes, 06189, France

  • Centre Cario - HPCA

    Plérin, Finistère, 22190, France

  • Centre Georges-François Leclerc

    Dijon, Côte d'Or, 21079, France

  • Institut du Cancer de Montpellier - Val d'Aurelle

    Montpellier, 34298, France

Conditions

Explore the condition pages connected to this study.