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New shot may beat aspirin at preventing deadly clots after knee surgery

NCT ID NCT07213778

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 32 times

Summary

This study tests an experimental drug called REGN7508 against aspirin to prevent dangerous blood clots after knee replacement surgery. About 2000 adults having a knee replaced will receive either REGN7508 or aspirin. The goal is to see which works better at stopping clots and is safe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Coastal Vascular Institute, PA

    RECRUITING

    Wilmington, North Carolina, 28401, United States

  • Eisenhower Medical Center

    RECRUITING

    Rancho Mirage, California, 92270, United States

  • Endeavor Clinical Trials

    RECRUITING

    San Antonio, Texas, 78240, United States

  • Endeavor Health

    RECRUITING

    Skokie, Illinois, 60076, United States

  • HD Research - Memorial Hermann Village

    RECRUITING

    Houston, Texas, 77043, United States

  • Holy Name Medical Center

    RECRUITING

    Teaneck, New Jersey, 07666, United States

  • Medical Research of Westchester - MPLUS Research Network

    RECRUITING

    Miami, Florida, 33165, United States

  • NextStage Clinical Research, St. Francis Medical Park

    RECRUITING

    Wichita, Kansas, 67214, United States

  • Ohio Clinical Trials

    RECRUITING

    Columbus, Ohio, 43212, United States

  • Phoenix Clinical Research

    RECRUITING

    Tamarac, Florida, 33321, United States

  • Sinai Hospital of Baltimore, Inc.

    RECRUITING

    Baltimore, Maryland, 21215, United States

  • Sky Ridge Medical Center

    RECRUITING

    Lone Tree, Colorado, 80124, United States

  • Spokane Joint Replacement Center

    RECRUITING

    Spokane, Washington, 99218, United States

  • The Ohio State University Wexner Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

  • The Orthopaedic Research Foundation, Inc.

    RECRUITING

    Indianapolis, Indiana, 46278, United States

  • University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45267, United States

Conditions

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