New shot may replace aspirin to stop deadly clots after knee surgery

NCT ID NCT07213778

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 29 times

Summary

This study tests an experimental drug called REGN7508 against aspirin to prevent dangerous blood clots in adults after knee replacement surgery. About 2000 participants will receive either the new drug or aspirin. The goal is to see which works better at preventing clots and related deaths.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SYMPTOMATIC VENOUS THROMBOEMBOLISM (VTE) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Coastal Vascular Institute, PA

    RECRUITING

    Wilmington, North Carolina, 28401, United States

  • Eisenhower Medical Center

    RECRUITING

    Rancho Mirage, California, 92270, United States

  • Endeavor Clinical Trials

    RECRUITING

    San Antonio, Texas, 78240, United States

  • Endeavor Health

    RECRUITING

    Skokie, Illinois, 60076, United States

  • HD Research - Memorial Hermann Village

    RECRUITING

    Houston, Texas, 77043, United States

  • Holy Name Medical Center

    RECRUITING

    Teaneck, New Jersey, 07666, United States

  • Medical Research of Westchester - MPLUS Research Network

    RECRUITING

    Miami, Florida, 33165, United States

  • NextStage Clinical Research, St. Francis Medical Park

    RECRUITING

    Wichita, Kansas, 67214, United States

  • Ohio Clinical Trials

    RECRUITING

    Columbus, Ohio, 43212, United States

  • Phoenix Clinical Research

    RECRUITING

    Tamarac, Florida, 33321, United States

  • Sinai Hospital of Baltimore, Inc.

    RECRUITING

    Baltimore, Maryland, 21215, United States

  • Sky Ridge Medical Center

    RECRUITING

    Lone Tree, Colorado, 80124, United States

  • Spokane Joint Replacement Center

    RECRUITING

    Spokane, Washington, 99218, United States

  • The Ohio State University Wexner Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

  • The Orthopaedic Research Foundation, Inc.

    RECRUITING

    Indianapolis, Indiana, 46278, United States

  • University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45267, United States

Conditions

Explore the condition pages connected to this study.