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Robot vs surgeon: can a machine better mend nerves?

NCT ID NCT07084207

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a robotic surgical system called Symani can safely and effectively repair damaged nerves in the hand. One hundred adults with a finger nerve injury will be randomly assigned to receive either robotic-assisted or traditional manual surgery. The main goal is to see how well sensation returns six months after the procedure, and to check for any serious problems during surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Symani® Surgical System (robotic-assisted surgery device)
What this could lead to
If successful, this could show that robotic-assisted microsurgery is a safe and effective option for repairing hand nerve injuries, potentially improving recovery of sensation.
What could go wrong
This is a relatively small, early-stage study (100 participants) comparing a new robotic device to standard manual surgery. The device may not improve outcomes over manual techniques, and there are always surgical risks like infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Pre-Operative Inclusion Criteria: 1. Adults, at the time of nerve injury aged from 18 to 70 years 2. Patient agrees to participate in the study, returns for all required follow-up visits, and has willingly provided written informed consent after receiving all information related to the study and its requirements 3. Complete loss of a nerve-specific receptive field of the finger 4. Patient with a clinical indication for a microsurgical nerve coaptation in nerve injury that can be repaired by end-to-end suturing 5. Patient with traumatic transection of one or more digit nerves distal to the carpal tunnel with sensory autonomous innervation areas on the finger or thumb tips 6. Investigator considers candidate acceptable for either conventional epineural suturing or robotic-assisted epineural suturing 7. The injury was treated within 10 days Exclusion Criteria: 1. Patients who are not capable and/or unwilling to provide informed consent 2. Clinically significant cardiovascular, digestive, respiratory, endocrine, liver or central nervous system disorders, previous mental disorders, or other disorders that may significantly affect the data collection or the ability to comply with the protocol per the investigators' discretion. 3. Currently enrolled in any other investigational clinical studies that the investigator believes may impact patient safety or outcomes 4. Patients belonging to vulnerable populations, such as pregnant women, or patients ineligible to participate for other reasons in the judgement of the investigator 5. Indication for bilateral nerve repair 6. Known impaired sensibility of the injured finger 7. Patients with implanted pacemaker 8. Replantation which includes bones Intra-Operative Inclusion Criteria Individuals will be included in the study if the following criteria are met intraoperatively: 1\. Verification of a sensory nerve lesion without a gap and presence of a nerve that could be sutured in end-to-end fashion Intra-Operative Exclusion Criteria Individuals will be excluded from participating in this study if any of the following criteria are met intraoperatively: 1\. Any presenting condition discovered intraoperatively that, in the opinion of the investigator, would

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Conditions

The condition(s) this trial relates to.

Peripheral Nerve Injuries traumatic neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • BG Klinik Ludwigshafen

    RECRUITING

    Ludwigshafen, Germany

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