Robot vs surgeon: can a machine better mend nerves?
NCT ID NCT07084207
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a robotic surgical system called Symani can safely and effectively repair damaged nerves in the hand. One hundred adults with a finger nerve injury will be randomly assigned to receive either robotic-assisted or traditional manual surgery. The main goal is to see how well sensation returns six months after the procedure, and to check for any serious problems during surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Symani® Surgical System (robotic-assisted surgery device)
- What this could lead to
- If successful, this could show that robotic-assisted microsurgery is a safe and effective option for repairing hand nerve injuries, potentially improving recovery of sensation.
- What could go wrong
- This is a relatively small, early-stage study (100 participants) comparing a new robotic device to standard manual surgery. The device may not improve outcomes over manual techniques, and there are always surgical risks like infection or nerve damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Dec 2025
- Expected to finish
-
Dec 2027
An estimate. End dates often move.
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Pre-Operative Inclusion Criteria: 1. Adults, at the time of nerve injury aged from 18 to 70 years 2. Patient agrees to participate in the study, returns for all required follow-up visits, and has willingly provided written informed consent after receiving all information related to the study and its requirements 3. Complete loss of a nerve-specific receptive field of the finger 4. Patient with a clinical indication for a microsurgical nerve coaptation in nerve injury that can be repaired by end-to-end suturing 5. Patient with traumatic transection of one or more digit nerves distal to the carpal tunnel with sensory autonomous innervation areas on the finger or thumb tips 6. Investigator considers candidate acceptable for either conventional epineural suturing or robotic-assisted epineural suturing 7. The injury was treated within 10 days Exclusion Criteria: 1. Patients who are not capable and/or unwilling to provide informed consent 2. Clinically significant cardiovascular, digestive, respiratory, endocrine, liver or central nervous system disorders, previous mental disorders, or other disorders that may significantly affect the data collection or the ability to comply with the protocol per the investigators' discretion. 3. Currently enrolled in any other investigational clinical studies that the investigator believes may impact patient safety or outcomes 4. Patients belonging to vulnerable populations, such as pregnant women, or patients ineligible to participate for other reasons in the judgement of the investigator 5. Indication for bilateral nerve repair 6. Known impaired sensibility of the injured finger 7. Patients with implanted pacemaker 8. Replantation which includes bones Intra-Operative Inclusion Criteria Individuals will be included in the study if the following criteria are met intraoperatively: 1\. Verification of a sensory nerve lesion without a gap and presence of a nerve that could be sutured in end-to-end fashion Intra-Operative Exclusion Criteria Individuals will be excluded from participating in this study if any of the following criteria are met intraoperatively: 1\. Any presenting condition discovered intraoperatively that, in the opinion of the investigator, would
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Nerve injury are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
BG Klinik Ludwigshafen
RECRUITINGLudwigshafen, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a Patient's playlist take the sting out of nerve testing?
- A 10-minute electric pulse during nerve surgery may speed up arm recovery
- Can a smart brain implant outsmart chronic pain?
- Magnetic pulses aim to ease nerve pain without drugs
- Biking your way to better nerve healing?
- Could a One-Hour shock boost nerve repair after severe arm injury?