Peer program fights stigma to boost HIV prevention in brazil
NCT ID NCT04114955
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a program called Manas por Manas to help transgender women in São Paulo, Brazil, overcome stigma and access HIV testing and PrEP (a daily pill that prevents HIV). The program included group sessions led by peers and one-on-one support. Researchers compared HIV testing and PrEP use between women who received the program and those who did not. The goal was to see if reducing stigma leads to better prevention.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- peer-led behavioral intervention (Manas por Manas)
- What this could lead to
- If successful, this approach could help reduce HIV infections among transgender women by making it easier to access testing and prevention pills.
- What could go wrong
- This is a completed trial, but results may not apply to other groups or regions. The intervention relies on peer support, which may not work everywhere.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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392 people
The number who actually took part.
- Started
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Dec 2020
- Finished
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Oct 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18 years or older; * assigned 'male' at birth but currently identify as female, transgender, transsexual, or travesti (a common identity term among trans women in Brazil); * not be known to be HIV positive; * be a resident of the São Paulo area; and * consent to study procedures, including consent to review their clinical records. Exclusion Criteria: * currently psychotic, suicidal, or manic; * known to be HIV-positive at enrollment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CRT - Centro de Referência e Treinamento DST/AIDS
São Paulo, Brazil
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SAE - Serviço de Assistência Especializada Campos Elíseos
São Paulo, Brazil
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