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Could a phosphate drug also stop kidney stones?

NCT ID NCT06481150

First seen Feb 06, 2026 · Last updated May 01, 2026 · Updated 7 times

Summary

This study tested whether Tenapanor, a drug already approved for kidney disease, can reduce oxalate absorption from food and lower the amount of oxalate in urine. Oxalate is a key component of many kidney stones. The study involved 18 healthy adults without a history of kidney stones, comparing urine oxalate levels while taking the drug versus a placebo. The goal is to find a new way to prevent kidney stones by blocking oxalate absorption in the gut.

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Contacts and locations

Locations

  • UT Southwestern Medical Center

    Dallas, Texas, 75390, United States

Conditions

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