Could a phosphate drug also stop kidney stones?

NCT ID NCT06481150

First seen Feb 06, 2026 · Last updated Jun 16, 2026 · Updated 16 times

Summary

This study tested whether Tenapanor, a drug approved for kidney disease, can reduce oxalate absorption from food and lower the risk of kidney stones. Eighteen healthy adults without a history of stones took the drug or a placebo, and their urine oxalate levels were compared. The goal was to see if blocking the same gut pathway used for phosphate also blocks oxalate.

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Contacts and locations

Locations

  • UT Southwestern Medical Center

    Dallas, Texas, 75390, United States

Conditions

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