Fly-fighting paint and larvicide aim to slash diarrhoea in south sudan camps
NCT ID NCT07272122
First seen Jun 26, 2026 · Last updated Jul 30, 2026 · Updated 3 times
Summary
This trial tests whether painting pit latrines with insecticidal paint or adding larvicide to breeding sites can reduce filth fly numbers and diarrhoeal disease in refugee camps in South Sudan. Over 5,600 people will take part across three camps. The study will measure diarrhoea cases in children under 5 and adults over 15, as well as fly counts. If successful, these simple tools could help prevent disease in harsh environments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- insecticidal paint (propoxur) and larvicide (diflubenzuron)
- What this could lead to
- If it works, this could provide a simple, low-cost way to prevent diarrhoeal diseases in refugee camps and other harsh settings.
- What could go wrong
- This is a large trial but results depend on real-world conditions like weather and camp hygiene. The interventions may not reduce flies enough to lower disease rates.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 5,556 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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1 year and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Individuals of either ≤5 years old or ≥15 years old all ages * Slept in camp ≥27 nights during any given month * Individual is not severely malnourished, sick, anemic (self-reported), has signs of clinical decompensation, and/or has any other chronic co-morbidities (e.g. HIV or cancer) * No plans for extended travel (\>1 month) outside of camp during study * Resides in an easily accessible dwelling and is present at time of enrolment * Not participating in another clinical trial investigating a vaccine, drug, medical device, or a medical procedure during the trial * Provision of informed consent form signed by the parent(s) or guardian (≤5s), able to give informed consent as an adult or able to give informed assent for children ≥15 years Exclusion Criteria: * Child \< 1 years old (due to breastfeeding) or aged \>5 and \<15 years old * Slept in camp \<27 nights during any given month * Individual is severely malnourished, sick, anemic, has signs of clinical decompensation, and/or has any other chronic co-morbidities (e.g. HIV or cancer) * Plans for extended travel (\>1 month) outside of camp during study * Not present at time of enrollment * Participating or planning to participate in another clinical trial investigating a vaccine, drug, medical device, or a medical procedure during the trial * No provision of informed consent form signed by the parent(s) or guardian (≤5s), unable to give informed consent as an adult or unable to give informed assent for children ≥15 years
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The MENTOR Initiative, Bunj Town, Maban
RECRUITINGBunj, Maban County, South Sudan
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Other studies related to the condition(s) this trial covers.