Could smart alerts end the 'Diagnostic Overshadowing' that endangers disabled patients?
NCT ID NCT06608758
First seen Aug 03, 2026 · Last updated Aug 06, 2026 · Updated 3 times
Summary
This study asks whether electronic health record prompts and targeted education can reduce diagnostic errors in people with disabilities. People with disabilities often have symptoms wrongly attributed to their disability, leading to missed or delayed diagnosis of serious conditions like sepsis or cancer. The trial will test these tools in a large group of patients aged 3 to 89, comparing outcomes for those with and without specific disabilities.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Electronic health record prompts and educational programs for healthcare professionals
- What this could lead to
- If effective, this could lead to tools and training that help doctors spot serious conditions in people with disabilities, reducing missed or delayed diagnoses.
- What could go wrong
- The study is large but focuses on understanding and implementing interventions; success depends on whether prompts and education actually change clinician behavior and improve outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 120,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2024
- Expected to finish
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Jul 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Cases: * Cases without disabilities are patients 3 - 89 years old without the following principal and secondary diagnoses (using associated ICD-10 codes): * Cases with disabilities are patients aged 3 - 89 years old with the following Principal and secondary diagnoses (using associated ICD-10 codes): * Mobility impairments: Spinal cord diseases, Spinal cord injuries, Injury to spinal cord nerves, Multiple sclerosis, Cerebral palsy, Dependence on enabling machines or devices, Need for caregiver related to mobility impairments * Severe Vision impairments * Severe Hearing impairments * Mental health: Person history mental and behavioral disorders, Major Depression, Severe bipolar disorder, Severe schizophrenia, Paranoia, Psychosis * Intellectual Disabilities * Autism
- Ages
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3 to 89 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: • Patients aged 3-89 who received billed charges Exclusion Criteria: * Patients under age 3 or over age 89. * Patients with secondary diagnosis of dementia as the population is already known to be at increased risk of diagnostic error
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Rush University Medical Center
RECRUITINGChicago, Illinois, 60612, United States
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