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Lower steroid dose before chemo may be just as safe, study hints

NCT ID NCT02776436

First seen Feb 22, 2026 · Last updated Apr 25, 2026 · Updated 9 times

Summary

This study looked at whether giving a lower dose of the steroid dexamethasone before the chemotherapy drug docetaxel is safe for people with breast or prostate cancer. The standard high dose can cause side effects like high blood sugar, mood changes, and immune suppression. Researchers tested different lower doses in 46 patients to find the smallest amount that still prevents allergic reactions and fluid retention. The goal is to reduce unnecessary side effects without compromising safety.

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Contacts and locations

Locations

  • Haga hospital

    The Hague, Netherlands

  • Leiden university medical center

    Leiden, Netherlands

  • Reinier de Graaf hospital

    Delft, Netherlands

Conditions

Explore the condition pages connected to this study.