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Quick cholesterol fixes may slash heart attack risk

NCT ID NCT07311941

Disease control Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether rapidly adjusting cholesterol-lowering medications, based on frequent blood tests, helps heart disease patients reach their LDL cholesterol targets faster. Researchers will enroll 1000 adults with coronary artery disease and monitor their cholesterol levels over a year. The goal is to see if this intensive approach reduces the risk of future heart attacks or strokes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
lipid-lowering medications (statins and other cholesterol drugs)
What this could lead to
If successful, this could show that a more intensive monitoring and treatment approach helps more heart patients reach their cholesterol goals and reduce the risk of future heart attacks or strokes.
What could go wrong
This is a registry study, not a randomized trial, so results may be influenced by patient selection. It focuses on cholesterol levels, not directly on preventing heart events, and the approach may not be feasible in all clinics due to resource needs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2024

Expected to finish

Jun 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients aged greater than 18 and who are admitted for a diagnosis of acute coronary syndrome (ACS) due to atherosclerotic coronary artery disease based on invasive coronary angiography will be recruited into this registry.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \>18 * (Cohort 1) Diagnosis of acute coronary syndrome due to atherosclerotic coronary artery disease * (Cohort 2) Diagnosis of chronic coronary syndrome due to atherosclerotic coronary artery disease Exclusion Criteria: * Inability to provide valid consent by the patient or his legal guardian * Diagnosis of ACS due to other causes than atherosclerotic coronary artery disease. * Psychiatric or severe neurological disorder, cirrhosis, or active malignancy leading to a life expectancy \< 6 months.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome cardiovascular disorder coronary atherosclerosis hyperlipidemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardio vascular disease Hyperlipidemia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Prince of Wales Hospital

    RECRUITING

    Shatin, New Terrritories, 999077, Hong Kong

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