New imaging trick could clear the bloody view during lung biopsies
NCT ID NCT07653945
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a special type of light, called red dichromatic imaging (RDI), can help doctors see more clearly after taking a tissue sample from the airway. Bleeding often blocks the view during bronchoscopic biopsies, making it hard to continue. Researchers will compare standard white light images with RDI images from the same procedure in 206 adults. No extra biopsies or changes to care are involved.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this imaging technique could help doctors perform bronchoscopic biopsies more safely and effectively by improving visibility after bleeding.
- What could go wrong
- This is an early observational study, not a treatment trial. It only tests image quality, not patient outcomes, and may not lead to changes in practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 206 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Jul 2026
An estimate. Start dates often move.
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will include adults aged 18 years or older who are scheduled to undergo clinically indicated bronchoscopic biopsy at participating centers. Eligible participants will have visible airway lesions during bronchoscopy, such as endobronchial masses, mucosal abnormalities, airway stenosis, or other abnormalities that require biopsy to determine the diagnosis. The study will not include healthy volunteers. Bronchoscopy and biopsy will be performed as part of routine clinical care, and paired white light imaging and red dichromatic imaging images will be collected during the same procedure after the first biopsy.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age ≥18 years. 2. Visible abnormal endobronchial lesion under bronchoscopy, including endobronchial neoplasm, mucosal abnormality, airway stenosis, or other lesion requiring biopsy to determine its nature. 3. Provision of informed consent to participate in this clinical study and signing of the informed consent form. Exclusion Criteria: 1. Presence of contraindications to bronchoscopy, such as severe cardiopulmonary disease, coagulation dysfunction (including patients receiving anticoagulant therapy and/or anticoagulant drugs who have not discontinued these drugs for more than 5 days before the examination), poor tolerance of anesthesia, psychiatric disease, or severe neurosis. 2. Intra-procedural decrease in SpO₂ or inability to tolerate bronchoscopy. 3. Obvious airway bleeding observed during bronchoscopy that may increase the risk of worsening the patient's condition. 4. Images that are obviously blurred or out of focus, or that contain severe reflection, bubbles, or instrument obstruction, making subsequent image analysis impossible. 5. Inability to cooperate with the study for any reason, or any other condition that the investigator considers unsuitable for study participation.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Airway lesion are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
7 sites. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Anhui Chest Hospital
Hefei, Hefei, 230022, China
-
Huzhou Central Hospital
Zhejiang, Huzhou, 313000, China
-
Lanxi Hospital of Traditional Chinese Medicine
Zhejiang, Jinhua, 321100, China
-
Shanghai Chest Hospital
Shanghai, Shanghai Municipality, 200030, China
-
The First Affiliated Hospital of Ningbo University
Zhejiang, Ningbo, 315000, China
-
The Second Hospital of Jiaxing
Zhejiang, Jiaxing, 314000, China
-
Zhoushan Hospital
Zhejiang, Zhoushan, 316000, China