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New chemo cocktail may boost survival in advanced rectal cancer

NCT ID NCT06048146

First seen Apr 08, 2026 · Last updated Apr 28, 2026 · Updated 1 time

Summary

This study tested a stronger three-drug chemotherapy (FOLFOXIRI) before surgery to remove rectal cancer that had spread to nearby lymph nodes. 180 patients were randomly assigned to get either this new combo or standard chemoradiation before surgery. The goal was to see if the stronger chemo could improve how long patients live without the cancer coming back. The study also looked for genetic markers that might predict who benefits most.

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Contacts and locations

Locations

  • Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College

    Beijing, Beijing Municipality, 100021, China

Conditions

Explore the condition pages connected to this study.