Could a chemo cocktail spare rectal cancer patients from radiation?
NCT ID NCT04215731
First seen Mar 10, 2026 · Last updated May 17, 2026 · Updated 9 times
Summary
This study compares two treatment approaches for people with high-risk locally advanced rectal cancer. One group gets a strong three-drug chemo plus a targeted therapy (bevacizumab), and only receives radiation if needed. The other group gets standard chemo followed by chemoradiation. The goal is to see if the stronger chemo can control the cancer just as well while avoiding the long-term side effects of radiation. About 582 adults will take part in this phase 3 trial.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Sixth Affiliated Hospital of Sun Yat-sen University
RECRUITINGGuangzhou, Guangdong, 510655, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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