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New hope for High-Risk leukemia: experimental enzyme combo trial opens

NCT ID NCT06918431

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 36 times

Summary

This study tests a new form of the drug asparaginase (made from a different bacterium) combined with standard chemotherapy in 53 high-risk adults aged 18–54 with newly diagnosed acute lymphoblastic leukemia or lymphoblastic lymphoma. The goal is to see if the combination is safe and helps control the disease. Participants will receive the drug during initial and follow-up chemotherapy phases.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope at Irvine Lennar

    NOT_YET_RECRUITING

    Irvine, California, 92618, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope at Phoenix

    RECRUITING

    Phoenix, Arizona, 85338, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic Foundation

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Email: •••••@•••••

    Contact

  • Memorial Sloan Kettering Cancer Center

    NOT_YET_RECRUITING

    New York, New York, 10065, United States

    Contact Email: •••••@•••••

    Contact

  • UC San Diego Moores Cancer Center

    NOT_YET_RECRUITING

    La Jolla, California, 92093, United States

    Contact Email: •••••@•••••

    Contact

  • UCLA / Jonsson Comprehensive Cancer Center

    NOT_YET_RECRUITING

    Los Angeles, California, 90095, United States

    Contact Email: •••••@•••••

    Contact

  • University of Chicago Comprehensive Cancer Center

    NOT_YET_RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.