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New nerve block technique may ease severe pain after shoulder surgery

NCT ID NCT06883279

Symptom relief Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two methods of giving a nerve block for shoulder surgery to see if one causes less severe 'rebound pain' when the block wears off. Rebound pain is a short but intense pain that can happen as the anesthesia fades. The researchers compared injecting the anesthetic directly between the nerve roots (intraplexus) versus around the nerves (extraplexus) in 85 adults. The goal is to find a way to make recovery less painful.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
local anesthetic (nerve block)
What this could lead to
If the extraplexus approach works better, it could offer a way to reduce severe rebound pain after shoulder surgery, making recovery more comfortable.
What could go wrong
This is a small, completed study with only 85 participants. The results may not apply to everyone, and the difference between the two approaches might be small or not meaningful in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

85 people

The number who actually took part.

Started

Mar 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-65 years. * Patients with ASA physical status I or II. * Patients planned for arthroscopic shoulder surgery in the lateral decubitus position with interscalene nerve block. Exclusion Criteria: * Patients who do not consent to participate in the study. * Block failure. * Language acquisition deficiency. * Obesity (body mass index \> 35 kg/m²). * Diabetes. * Psychiatric disorders. * Central nervous system diseases. * Vestibular diseases. * Presence of neuropathy and paralysis. * Pregnancy. * Previous open shoulder surgery. * Allergy to local anesthetics. * Coagulopathy. * Severe thrombocytopenia. * Infection at the puncture site. * Pre-existing neuropathy in the limb to be operated. * Use of dexamethasone. * Use of opioid and antiemetic medications before surgery. * Severe cardiopulmonary disease. * Low baseline oxygen saturation. * Conditions that prevent cooperation in the postoperative period (e.g., mental retardation, delirium).

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative Shoulder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia Pain, postoperative Pain, shoulder

Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    Ankara, Ankara, Çankaya, 06800, Turkey (Türkiye)

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