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Real-world data on two-drug combo for hard-to-treat hodgkin lymphoma

NCT ID NCT07145125

First seen Nov 21, 2025 · Last updated Jun 22, 2026 · Updated 28 times

Summary

This study looked at 222 adults with Hodgkin lymphoma that had returned or not responded to first treatment. Researchers wanted to see how well the combination of brentuximab vedotin and bendamustine worked in everyday medical practice. They measured how long patients stayed free of progression and overall survival, along with side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CH de la Côte Basque, service Hématologie Clinique

    Bayonne, France

  • CHU de Bordeaux, service Hématologie Clinique et Thérapie cellulaire

    Bordeaux, France

  • CHU de Caen, service Hématologie Clinique

    Caen, France

  • CHU de Toulouse, service Hématologie Clinique

    Toulouse, France

  • Institut Paoli Calmettes, service Hématologie Clinique

    Marseille, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

brentuximab vedotin and bendamustine

What this could lead to

If results are positive, this could confirm a useful treatment option for people whose Hodgkin lymphoma has come back or not responded to initial therapy.

What could go wrong

This is a real-world observational study, not a controlled trial, so results may be less reliable. The combination also has known side effects like nerve damage and low blood counts.

Conditions

The condition(s) this trial relates to.

Hodgkins lymphoma Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.