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New study observes how breast cancer patients fare on Triple-Drug therapy

NCT ID NCT07151911

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 34 times

Summary

This observational study follows 100 high-risk early breast cancer patients who are already taking a combination of abemaciclib, olaparib, and endocrine therapy as part of their routine care. Researchers will track which treatments are chosen and how patients' quality of life changes over 5 years. The goal is to describe real-world patterns, not to test a new drug.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Ospedaliero Universitaria Policlinico di Modena

    RECRUITING

    Modena, Modena, 41124, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

abemaciclib, olaparib, and endocrine therapy

What this could lead to

If successful, this study could help doctors better understand which high-risk early breast cancer patients benefit most from specific drug combinations, improving personalized treatment decisions.

What could go wrong

This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may be influenced by patient selection and real-world variability.

Conditions

The condition(s) this trial relates to.

breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.