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Real-World check: Orkambi's safety and effectiveness in 852 CF patients

NCT ID NCT03475381

First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 24 times

Summary

This study followed 852 people with cystic fibrosis (ages 12 and older) who were taking the drug Orkambi outside of a clinical trial. Researchers tracked how many stopped treatment, why, and measured lung function, nutrition, and infections over one year. The goal was to see how well the drug works in real-life settings, not just in controlled trials.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Adult CF center, Service de Pneumologie, Cochin Hospital

    Paris, Paris, 75006, France

Conditions

Explore the condition pages connected to this study.