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New exercise approach may boost fitness and balance in stroke survivors

NCT ID NCT04042961

Symptom relief Sponsor: Toronto Rehabilitation Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether reactive balance training—exercises that involve sudden pushes, pulls, or quick movements—can improve aerobic fitness and leg strength in people who had a stroke at least six months ago. The researchers expected that this training would be as good as standard aerobic and strength exercises for fitness, and possibly better for balance. The study enrolled 28 community-dwelling adults and was terminated early, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Reactive balance training (a type of exercise that uses pushes, pulls, and agility tasks to improve balance reactions)
What this could lead to
If successful, this could show that reactive balance training is a time-efficient way to improve both fitness and balance after a stroke.
What could go wrong
The study was terminated early and enrolled only 28 people, so results may be limited. It is also a small, single-site trial, so findings may not apply to all stroke survivors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

28 people

The number who actually took part.

Started

Sep 2019

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Community-dwelling adults with chronic stroke (\>6 months post-stroke). * Able to stand independently without upper-limb support for \>30 seconds. * Able to tolerate at least 10 postural perturbations while wearing a safety harness. Exclusion Criteria: * \>2.1m tall and/or weighing \>150kg (limits of the safety harness system). * Other neurological condition that could affect balance control (e.g., Parkinson's disease). * Lower extremity amputation. * Cognitive, language or communication impairments affecting understanding instructions. * Recent (last 6 months) significant illness, injury or surgery. * Severe osteoporosis, defined by diagnosis of osteoporosis with fracture. * Severe uncontrolled hypertension, or uncontrolled diabetes. * Contraindications to exercise testing, such as symptomatic aortic stenosis, complex life-threatening arrhythmias, unstable angina, or orthostatic blood pressure decrease of \>20 mmHg with symptoms. * Acute or chronic illness or injury likely to be exacerbated by exercise (e.g., recent lower-extremity fracture). * Currently attending in- or out-patient physiotherapy, in which they receive aerobic training, balance training or strength training for lower limb. * Significant exercise participation: current physical activity levels that meet the recommended guidelines (at least 150 minutes of moderate-to-vigorous or at least 75 minutes of vigorous physical activity/week) as calculated using the moderate and vigorous components of the Leisure Time Exercise Questionnaire (LTEQ) in the month prior to starting the study. * Received perturbation training at Toronto Rehab \<1 year previously.

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cva (cerebrovascular accident)

Contacts and locations

Locations

  • Toronto Rehabilitation Institute

    Toronto, Ontario, M5G 2A2, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.