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New drug targets rare lung disease in early trial

NCT ID NCT06633757

First seen Oct 31, 2025 · Last updated May 23, 2026 · Updated 29 times

Summary

This study tested an experimental drug called RCT1100 in 14 adults with primary ciliary dyskinesia (PCD) caused by a specific gene change (DNAI1). PCD makes it hard for the lungs to clear mucus, leading to frequent infections. The goal was to see if RCT1100 is safe and can improve how well the lungs clear mucus. This is an early-stage trial, so results will help plan future studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Copenhagen University Hospital - Rigshospitalet

    Copenhagen, 2100, Denmark

  • Münster University Hospital, Albert-Schweitzer-Campus 1

    Münster, North Rhine-Westphalia, 48149, Germany

  • UNC

    Chapel Hill, North Carolina, 27514, United States

Conditions

Explore the condition pages connected to this study.