Experimental drug aims to clear lungs in rare genetic disease

NCT ID NCT06633757

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 26 times

Summary

This early-stage study tested an experimental drug called RCT1100 in 14 adults with primary ciliary dyskinesia (PCD) caused by a specific genetic change in the DNAI1 gene. The goal was to see if the drug could improve how the lungs clear mucus and to check for safety. The results will help plan future studies.

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Contacts and locations

Locations

  • Copenhagen University Hospital - Rigshospitalet

    Copenhagen, 2100, Denmark

  • Münster University Hospital, Albert-Schweitzer-Campus 1

    Münster, North Rhine-Westphalia, 48149, Germany

  • UNC

    Chapel Hill, North Carolina, 27514, United States

Conditions

Explore the condition pages connected to this study.