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Gene-Guided therapy may outperform standard care for rare cancers

NCT ID NCT06855134

First seen May 13, 2026 · Last updated May 24, 2026 · Updated 4 times

Summary

This study compares two approaches for treating advanced rare cancers: one where treatment is chosen based on a detailed genetic analysis of the tumor, and another where standard treatment is given first, with genetic testing used later if needed. About 946 adults with rare cancers that have spread or cannot be cured will take part. The goal is to see if the genetic-guided approach helps people live longer without their cancer getting worse.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Charité Berlin

    RECRUITING

    Berlin, 10117 Berlin, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

    Contact

  • Comprehensive Cancer Center , LMU München

    NOT_YET_RECRUITING

    München, 81377, Germany

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Comprehensive Cancer Center Ostbayern (CCCO) Universitätsklinikum Regensburg,

    RECRUITING

    Regensburg, 93053, Germany

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Medizinische Fakultät der TU Dresden

    RECRUITING

    Dresden, 01307, Germany

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

    Contact

  • Robert Bosch Krankenhaus Stuttgart

    RECRUITING

    Stuttgart, 70376, Germany

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Uniklinikum Erlangen

    RECRUITING

    Erlangen, 91054, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Universitäts-Klinikum Köln

    RECRUITING

    Cologne, 50937, Germany

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitätsklinikum Augsburg

    RECRUITING

    Augsburg, 86156, Germany

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Universitätsklinikum Freiburg, Tumorzentrum Freiburg - CCCF

    NOT_YET_RECRUITING

    Freiburg im Breisgau, 79106, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Universitätsklinikum Hamburg-Eppendorf (UKE)

    NOT_YET_RECRUITING

    Hamburg, 20246, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Universitätsklinikum Heidelberg

    RECRUITING

    Heidelberg, 69120, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Universitätsklinikum Tübingen

    RECRUITING

    Tübingen, 72076, Germany

    Contact Phone: •••-•••-••••

    Contact

    Contact

  • Universitätsklinikum Ulm

    RECRUITING

    Ulm, 89081, Germany

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Universitätsklinium Würzburg

    RECRUITING

    Würzburg, 97080, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Universitätsmedizin Essen

    NOT_YET_RECRUITING

    Essen, 45147, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Universitätsmedizin der Johannes Gutenberg- Universität Mainz

    NOT_YET_RECRUITING

    Mainz, 55131, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.