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New hope for hard-to-treat pancreatic cancer: targeted drug combo enters phase 3 trial

NCT ID NCT07621718

First seen Jun 06, 2026 · Last updated Jun 06, 2026

Summary

This study tests whether adding an experimental drug called zoldonrasib to standard chemotherapy helps people with a specific genetic form of metastatic pancreatic cancer (KRAS G12D mutation) live longer without their cancer growing. About 670 adults with advanced pancreatic cancer that has spread will receive either the drug combo or a placebo plus chemo. The goal is to see if the targeted therapy improves survival and slows disease progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Piedmont Healthcare

    RECRUITING

    Atlanta, Georgia, 30318, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

pancreatic ductal adenocarcinoma Pancreatic Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.