New MRI technique could sharpen views of gynecologic tumors
NCT ID NCT04893434
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new type of DCE-MRI that takes pictures faster and reduces blurring from movement. The goal is to see if it gives clearer images of gynecologic tumors than traditional MRI. About 24 women with gynecologic cancer and healthy volunteers will take part. The new scan uses a standard MRI machine and an FDA-approved contrast dye.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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24 people
The number who actually took part.
- Started
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May 2021
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Healthy volunteers (for SA1) will be entered into the study if they meet the following criteria: * Women aged 18 years or older. * Willing and able to provide informed consent Patients (for SA2) will be entered into the study if they meet the following criteria: * Women aged 18 years or older. * Gynecologic cancer undergoing standard of care pelvic MRI prior to treatment * Willing and able to provide informed consent and adhere to the study visit schedule and plan as specified in this protocol. Exclusion Criteria: Healthy volunteers (SA1) and patients (SA2) exclusion criteria: * History of allergic reactions to gadolinium-based contrast agents (GBCAs) * Women of childbearing potential (WOCBP) must not be pregnant. * Women must not be breastfeeding. * Contraindications/risk factors to 3T MRI as per assessed by our departmental "Comprehensive MRI Screening Questionnaire" and "MRI Contrast Dye Questionnaire" (e.g. risk factors associated with magnetic field such as cardiac pacemakers, defibrillators or other devices as per standard institutional policy; and risk factors associated with GBCM such as diabetes, dialysis, breastfeeding)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan Kettering Bergen (All Protocol Activities)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Nassau (All Protocol Activities)
Uniondale, New York, 11553, United States
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