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Can a CT scan spot hidden lung damage in rheumatoid arthritis?

NCT ID NCT07174102

Knowledge-focused Sponsor: Azienda Unita Sanitaria Locale di Piacenza Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study will examine chest CT scans from 500 adults with rheumatoid arthritis, connective tissue diseases, or idiopathic pulmonary fibrosis to better understand lung disease patterns. Researchers want to see which scan features are most common in rheumatoid arthritis-related interstitial lung disease and how they differ from other lung conditions. Participants will have their existing scans reviewed by a specialist, and some may have follow-up scans after two years to track changes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High resolution computed tomography (HRCT)
What this could lead to
If successful, this could help doctors identify rheumatoid arthritis-related lung disease earlier and more accurately using CT scans.
What could go wrong
This is an observational study, not a treatment trial. It will not test any new drug or therapy, and results may not change current care directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Jan 2035

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

RA patients or with idiopathic pulmonary fibrosis and other connective tissue diseases

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients able to give their informed consent * at least aged 18 years * patients undergoing High-Resolution Computed Tomography (HRCT) for clinical needs at any point in their medical history * patients with a diagnosis of rheumatoid arthritis, idiopathic pulmonary fibrosis or connective tissue disease Exclusion criteria: Patients younger than 18 and unable to give their informed consent.

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Conditions

The condition(s) this trial relates to.

connective tissue disorder idiopathic pulmonary fibrosis interstitial lung disease rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Connective tissue disease (CTD) Idiopathic pulmonary fibrosis (IPF) Interstitial lung disease due to systemic disease (disorder) Reumatoid arthritis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    5 sites in 2 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • AUSL-IRCCS di Reggio Emilia

    RECRUITING

    Reggio Emilia, Italy

  • Institute of Rheumatology, Na Slupi 4

    NOT_YET_RECRUITING

    Prague, Czechia

  • Local Health Unit ("Azienda Unità Sanitaria Locale", AUSL) of Piacenza

    RECRUITING

    Piacenza, 29121, Italy

  • SC Malattie Apparato Respiratorio, Azienda Policlinico di Modena

    RECRUITING

    Modena, Italy

  • UOC Reumatologia, Arcipedale Sant'Anna

    RECRUITING

    Ferrara, Italy

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