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New radiation approach aims to treat liver cancer in patients with damaged livers

NCT ID NCT02626312

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 34 times

Summary

This early-phase trial tested radiation therapy in 36 patients with liver cancer (hepatocellular carcinoma, cholangiocarcinoma, or liver metastases) who also had impaired liver function due to cirrhosis, chemotherapy, or surgery. The goal was to find the safest dose and see if it could control tumors. The study was terminated early, but data may still inform future treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy

What this could lead to

If successful, this could help find a safer radiation dose for liver cancer patients with liver damage, potentially improving tumor control.

What could go wrong

This is an early phase I trial with only 36 participants, so results may not apply to everyone. The trial was terminated, and side effects could be significant due to already impaired liver function.

Conditions

The condition(s) this trial relates to.

cholangiocarcinoma Fibrosis hepatocellular carcinoma liver cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.