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New hydrogel aims to speed recovery after brain surgery

NCT ID NCT05898074

First seen Apr 11, 2026 · Last updated Jun 23, 2026 · Updated 13 times

Summary

This study tests a special hydrogel (PuraGel) placed inside the nose after skull base surgery to see if it helps the surgical site heal faster and reduces pain. Thirty adults having this surgery will be randomly assigned to get either the hydrogel or a standard silicone splint. Doctors will check healing and pain levels at 1, 4, and 12 weeks after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Indiana University

    RECRUITING

    Indianapolis, Indiana, 46202, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PuraGel (RADA16) Hydrogel

What this could lead to

If it works, this could lead to faster healing and less pain after skull base surgery.

What could go wrong

This is a small early study with only 30 people, so results may not apply to everyone. The hydrogel is a device, not a drug, so benefits may be modest.

Conditions

The condition(s) this trial relates to.

cerebrospinal fluid leak Hypertrophy skull base neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.