New hope for blood cancer patients: experimental drug targets resistant MDS
NCT ID NCT05308264
First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 26 times
Summary
This study tests an experimental drug called R289 in adults with lower-risk myelodysplastic syndromes (MDS) whose disease has not improved with standard therapies. The main goals are to check the drug's safety and see if it can reduce or eliminate the need for red blood cell transfusions. About 86 participants will take R289 pills, and researchers will monitor side effects and blood count improvements.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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Duke Cancer Institute
NOT_YET_RECRUITINGDurham, North Carolina, 27705, United States
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Ichan School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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Intermountain Healthcare
RECRUITINGSalt Lake City, Utah, 84009, United States
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Mount Sinai Medical Center
WITHDRAWNMiami Beach, Florida, 33140, United States
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Oncology Clinical Research Referral Office
RECRUITINGHackensack, New Jersey, 07601, United States
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Rutgers Cancer Institute of New Jersey
WITHDRAWNNew Brunswick, New Jersey, 09083, United States
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Stanford Cancer Institute
NOT_YET_RECRUITINGPalo Alto, California, 94304, United States
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The Ohio State University Comprehensive Cancer Center
NOT_YET_RECRUITINGColumbus, Ohio, 43210, United States
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University of California, Irvine
RECRUITINGOrange, California, 92868, United States
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University of California, Los Angeles
RECRUITINGLos Angeles, California, 90095, United States
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University of Miami
RECRUITINGMiami, Florida, 33136, United States
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University of Texas, Southwestern
RECRUITINGDallas, Texas, 75390, United States
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WashU Medicine
NOT_YET_RECRUITINGSt Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.