New drug R289 offers hope for blood disorder patients who failed other therapies
NCT ID NCT05308264
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an experimental drug called R289 in about 86 adults with a type of blood cancer called lower-risk myelodysplastic syndromes (MDS). Participants must have tried other standard treatments without success. The main goal is to check the drug's safety and side effects, and also to see if it can reduce or eliminate the need for red blood cell transfusions. The study is currently recruiting.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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Duke Cancer Institute
NOT_YET_RECRUITINGDurham, North Carolina, 27705, United States
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Ichan School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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Intermountain Healthcare
RECRUITINGSalt Lake City, Utah, 84009, United States
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Mount Sinai Medical Center
WITHDRAWNMiami Beach, Florida, 33140, United States
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Oncology Clinical Research Referral Office
RECRUITINGHackensack, New Jersey, 07601, United States
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Rutgers Cancer Institute of New Jersey
WITHDRAWNNew Brunswick, New Jersey, 09083, United States
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Stanford Cancer Institute
NOT_YET_RECRUITINGPalo Alto, California, 94304, United States
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The Ohio State University Comprehensive Cancer Center
NOT_YET_RECRUITINGColumbus, Ohio, 43210, United States
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University of California, Irvine
RECRUITINGOrange, California, 92868, United States
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University of California, Los Angeles
RECRUITINGLos Angeles, California, 90095, United States
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University of Miami
RECRUITINGMiami, Florida, 33136, United States
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University of Texas, Southwestern
RECRUITINGDallas, Texas, 75390, United States
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WashU Medicine
NOT_YET_RECRUITINGSt Louis, Missouri, 63110, United States