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Kneecap pain study probes muscle oxygen use during exercise

NCT ID NCT07139158

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how the quadriceps (thigh) muscle uses oxygen in people with patellofemoral pain (pain around the kneecap) compared to pain-free individuals. Researchers measured muscle oxygenation using a light-based device during activities like squatting and stair climbing. The goal was to understand if poor oxygen use contributes to ongoing pain and muscle dysfunction.

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Study facts

What this study's own registry entry says, in plain language.

Participants

41 people

The number who actually took part.

Started

Aug 2025

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Twenty-one patients with patellofemoral pain and 20 pain-free controls will be conducted at Ankara Medipol University, Faculty of Health Sciences, Physiotherapy and Rehabilitation Department.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18-40 years of age * pain around or behind the patella, which is aggravated by at least one activity that loads the patellofemoral joint during weight bearing on a flexed knee (e.g., squatting, stair ambulation, jogging/running, hopping/jumping) * the pain persist for at least four months, and be rated at ≥ 3/10 on the Numeric Pain Rating Scale (NPRS) * vastus medialis muscle adipose tissue thickness \<20 mm Pain-free controls were age- and gender-matched, with vastus medialis muscle adipose tissue thickness \<20 mm. Exclusion Criteria: * a history of joint surgery * meniscal and/or ligament injuries * patellar instability, congenital patellar subluxation/dislocation * any cardiovascular, congenital, or musculoskeletal disorders that could interfere with the assessment

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Conditions

The condition(s) this trial relates to.

Kinesiophobia Motor Activity patellofemoral pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ankara Medipol University

    Ankara, Altındağ, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.