Knee surgery aftermath: thigh muscle 'Shutdown' may slow recovery
NCT ID NCT06096792
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at why the quadriceps (thigh) muscle sometimes stops working properly after total knee replacement surgery. Researchers measured muscle inhibition in 20 patients during their hospital stay and tracked their recovery for 6 weeks. The goal was to understand how this muscle problem affects walking and daily activities, which could help improve rehabilitation plans.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better plan rehabilitation after knee replacement surgery, potentially improving recovery.
- What could go wrong
- This is a small, completed observational study with only 20 participants, so results may not apply to everyone. It does not test a treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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20 people
The number who actually took part.
- Started
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Oct 2024
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients who underwent total knee arthroplasty at Hacettepe University faculty of medicine
- Ages
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50 to 75 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 50 and 75 years. * Have undergone unilateral total knee arthroplasty surgery due to osteoarthritis. * Hemodynamically stable post-surgery. * Willing to participate in the study. Exclusion Criteria: * Having any neurological or oncological issues. * Having undergone revision surgery. * Having a history of cardiovascular surgery.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hacettepe University
Ankara, Samanpazari, 06100, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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