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Knee surgery aftermath: thigh muscle 'Shutdown' may slow recovery

NCT ID NCT06096792

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at why the quadriceps (thigh) muscle sometimes stops working properly after total knee replacement surgery. Researchers measured muscle inhibition in 20 patients during their hospital stay and tracked their recovery for 6 weeks. The goal was to understand how this muscle problem affects walking and daily activities, which could help improve rehabilitation plans.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better plan rehabilitation after knee replacement surgery, potentially improving recovery.
What could go wrong
This is a small, completed observational study with only 20 participants, so results may not apply to everyone. It does not test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

20 people

The number who actually took part.

Started

Oct 2024

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who underwent total knee arthroplasty at Hacettepe University faculty of medicine

Ages

50 to 75 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 50 and 75 years. * Have undergone unilateral total knee arthroplasty surgery due to osteoarthritis. * Hemodynamically stable post-surgery. * Willing to participate in the study. Exclusion Criteria: * Having any neurological or oncological issues. * Having undergone revision surgery. * Having a history of cardiovascular surgery.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hacettepe University

    Ankara, Samanpazari, 06100, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.