Can a higher voltage turn down chronic neck pain?
NCT ID NCT07744438
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This trial compares two voltage settings (45 V vs 60 V) of pulsed radiofrequency, a minimally invasive procedure that uses electrical pulses to calm overactive nerves, for people with chronic neck pain caused by a herniated disc. Participants will receive the procedure on the cervical dorsal root ganglion, and researchers will measure pain intensity and neck-related disability over time. The goal is to see if a higher voltage provides better pain relief and improved function without increasing side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Pulsed radiofrequency applied to the cervical dorsal root ganglion at either 45 volts or 60 volts
- What this could lead to
- If successful, this could help determine the optimal voltage setting for pulsed radiofrequency, potentially improving pain relief and function for people with chronic neck pain.
- What could go wrong
- This is a small, early-stage comparison, and results may not apply to all patients. The procedure carries risks like temporary nerve irritation or discomfort, and the higher voltage may not prove more effective.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 58 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Unilateral cervical radicular pain consistent with cervical disc herniation. * Pain intensity of ≥6 on the Numerical Rating Scale (NRS). * Radicular pain persisting for at least 3 months. * MRI evidence of lower cervical nerve root compression consistent with clinical findings. * Inadequate response to conservative treatment, including analgesic medications and physical therapy. * Completion of cervical dorsal root ganglion pulsed radiofrequency (PRF) treatment. Exclusion Criteria: * Bilateral upper extremity pain or predominant axial neck pain. * Cervical spinal stenosis, spondylolisthesis, cervical myelopathy, or other structural spinal disorders causing radicular pain. * Previous cervical spine surgery at the target level. * Cognitive impairment preventing reliable outcome assessment. * Active local or systemic infection. * Coagulopathy or inability to discontinue anticoagulant/antiplatelet therapy for the procedure. * Severe hepatic or renal failure. * Pregnancy. * Unstable psychiatric disorders. * Any condition that could interfere with completion of follow-up evaluations.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ankara Etlik City Hospital
RECRUITINGAnkara, Turkey (Türkiye)
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