Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Can a gentle electric field fix a racing heart?

NCT ID NCT07727330

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests whether a procedure called pulsed field ablation can safely treat ventricular arrhythmias—abnormal heart rhythms that can be life-threatening. About 30 people with frequent premature heartbeats or ventricular tachycardia will receive the treatment using a special catheter. The study will check if the arrhythmia disappears or drops by at least 80% right after the procedure and again six months later.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a procedure called pulsed field ablation using a special catheter
What this could lead to
If it works, this could offer a new, safer way to correct dangerous heart rhythm problems without the heat or cold used in standard ablation.
What could go wrong
This is a small, early-stage study with only 30 people, so results may not apply to everyone. Risks include heart damage, bleeding, or the arrhythmia returning.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Apr 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Participants must meet all of the following criteria: 1. Age 18 to 75 years, inclusive. 2. Diagnosis of ventricular arrhythmia with an indication for catheter ablation, and scheduled to undergo pulsed field ablation, meeting one of the following conditions: 1. Frequent premature ventricular contractions, defined as a premature ventricular contraction burden greater than 10% of total heartbeats on 24-hour Holter monitoring; 2. Sustained monomorphic ventricular tachycardia; 3. History of malignant ventricular arrhythmias, including sustained polymorphic ventricular tachycardia, ventricular flutter, or ventricular fibrillation, with an indication for catheter ablation. 3. For participants with an indication for implantable cardioverter-defibrillator implantation, the participant has already received an implantable cardioverter-defibrillator or agrees to undergo implantable cardioverter-defibrillator implantation in the near future. 4. Able and willing to provide written informed consent and comply with all study follow-up requirements. Exclusion Criteria: 1. Presence of atrial arrhythmias before the procedure that cannot be treated using the study device. 2. Ventricular arrhythmias caused by electrolyte disturbance, reversible causes, or non-cardiac causes. 3. Severe left ventricular enlargement, defined as left ventricular anteroposterior diameter greater than 80 mm. 4. Left ventricular ejection fraction of 35% or less. 5. New York Heart Association functional class III or IV. 6. Previous cardiac surgery, including patent foramen ovale closure, left atrial appendage closure, cardiac valve repair or replacement, or other cardiac surgery that makes the participant unsuitable for catheter ablation. 7. Significant congenital cardiac anatomical abnormalities that prevent the ablation catheter from accessing the target ablation area. 8. Planned cardiac surgery or other major surgery within the next 12 months that may affect ablation treatment, including heart transplantation, left atrial appendage closure, or patent foramen ovale closure. 9. Intracardiac thrombus, myxoma, occlusion device, or other condition that may interfere with catheter insertion or manipulation. 10. Severe vascular access obstruction, such as an implanted inferior vena cava filter or mural thrombus. 11. Uncontrolled hypertension, defined as persistent systolic blood pressure of 180 mmHg or higher or persistent diastolic blood pressure of 110 mmHg or higher. 12. Severe restrictive or obstructive pulmonary disease or chronic respiratory disease that, in the investigator's judgment, makes the participant unsuitable for cardiac intervention. 13. Obvious bleeding tendency or hematologic disease. 14. Untreated or uncontrolled hyperthyroidism or hypothyroidism. 15. Acute or severe systemic active infection, significant hepatic or renal dysfunction defined as ALT, AST, or creatinine greater than twice the upper limit of normal, malignancy, or end-stage disease. 16. Unstable angina or acute myocardial infarction within 3 months before enrollment. 17. Percutaneous coronary intervention or coronary artery bypass grafting within 3 months before enrollment. 18. Stroke or transient ischemic attack within 3 months before enrollment. 19. Thromboembolic disease. 20. Clear contraindication to interventional procedures or ablation as determined by the investigator. 21. Pregnancy, lactation, or planned pregnancy during the study period. 22. Participation in another drug or medical device clinical trial within 3 months before enrollment. 23. Any condition that, in the investigator's judgment, makes the participant unsuitable for participation in this clinical study.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Sustained monomorphic ventricular tachycardia are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.