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Which dental filling material keeps molars alive and Pain-Free?

NCT ID NCT06784622

Symptom relief Sponsor: TC Erciyes University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 11, 2026 · Last updated Sep 11, 2026

Summary

Researchers compare two materials used in pulpotomy, a procedure that removes inflamed pulp from a tooth and covers the remaining tissue. Adults with deep cavities and signs of pulp inflammation in lower first or second molars receive either BIO MTA+ or Well-Root PT. The study measures postoperative pain using a visual pain scale and checks whether the teeth stay vital.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Two dental materials used in pulpotomy: a mineral trioxide aggregate (BIO MTA+) and a bioceramic sealer (Well-Root PT)
What this could lead to
If one material causes less pain and better preserves tooth vitality, dentists could choose it more often for pulpotomy in adult molars.
What could go wrong
This is a small, single-center study. Pain scores are subjective, and results may not apply to other dentists, materials, or tooth types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

58 people

The number who actually took part.

Started

Jan 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over 18 years of age with no significant health problems. * Restorable and periodontally healthy teeth. * Teeth with complete root development. * Teeth with cold sensitivity and positive response to electric pulp testing. * Lower jaw first and second molars with deep/extremely deep caries detected on periapical radiographs. Exclusion Criteria: * Patients with systemic diseases or allergic reactions * Teeth with open apex * Carious teeth that do not respond to pulp sensitivity tests * Teeth without signs of bleeding after opening the pulp chamber. * Detection of periodontal pockets with a depth greater than 4 mm. * Teeth with suspected cracks or crown fractures. * Severely damaged teeth * Teeth whose bleeding cannot be controlledTeeth with open apex

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Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute pulpitis

Contacts and locations

Locations

  • Erciyes University Faculty of Dentistry

    Kayseri, Melikgazi, 38039, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.