New study brings lung rehab to africa: can exercise programs help millions?
NCT ID NCT07602673
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a supervised exercise and education program (pulmonary rehabilitation) can help people with long-term lung diseases like COPD, asthma, and post-TB lung damage in Nigeria, South Africa, and Cameroon. Researchers will enroll 90 patients to see if the program improves their ability to walk and their quality of life. The goal is to find out if this type of care can work in low-resource settings.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male and female adults (\>= 18 years) with specified clinical diagnosis (typically by detailed clinical history \[persistent symptoms for ≥6 months\] plus spirometry and/or other available tests, e.g., chest X-ray\] * Individuals with CRDs, specifically COPD, asthma or post-tuberculosis lung disorder * Patients with CRDs who have an indication for PR (specifically, these are patients with moderate to severe staged disease who present with reduced exercise/functional capacity, poor quality of life, high disease symptoms, particularly dyspnea) and are medically fit to undergo exercise training (which is to be determined by pre-exercise screening and field tests). * Patients with CRDs attending regular follow-up in the respiratory clinics of the selected centres. * Patients who are willing and able to provide written or oral (audio recorded) informed consent * All levels (primary, secondary, and tertiary) of healthcare professionals, including doctors, nurses, physiotherapists, respiratory therapists, medical assistants, healthcare administrators, pulmonologists, and other formal practitioners working in primary, secondary, and tertiary care settings, who provide services to patients who may potentially require PR. * Relevant stakeholders, including policymakers, religious leaders, sports leaders, the pharmaceutical industry, social workers, managers, and hospital/practice owners. * Willing and able to provide written or oral (audio recorded) informed consent. Exclusion Criteria: * Patients with other significant chronic co-morbidities such as heart failure, ischemic heart disease, DM, and confusion/dementia * Pregnant women * Co-morbidity that is a contraindication to PR (e.g., unstable angina, aortic aneurysm, recent myocardial infarction, acute infection, etc.) * Significant cognitive or physical impairment preventing participation in PR * Active pulmonary tuberculosis vi. Patient with current or recent disease exacerbations * Non-respiratory cause for symptoms (e.g., breathlessness due to heart failure, anaemia) * Unable to participate in exercise (e.g., due to severe arthritis or paralysis) * Undertaken PR within one year. * Unwilling to participate in the study. * Unable to give written or oral (audio recorded) informed consent * Healthcare professionals who are not involved in the care of patients who require PR, e.g., midwives * Having a conflict of interest that may influence the outcome * Unable and unwilling to give written or oral (audio recorded) informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites in 3 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Chris Hani Baragwanath Academic Hospital
Johannesburg, Gauteng, 2041, South Africa
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Lagos State University Hospital
Lagos, Lagos, 00234, Nigeria
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Regional Hospital Limbe
Yaoundé, Cameroon
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