Can we predict a deadly lung crisis? new study seeks answers
NCT ID NCT07653958
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This observational study will follow 5000 people with pulmonary hypertension to understand a severe complication called pulmonary hypertension crisis. Researchers will collect medical data and samples to build a risk prediction tool. The goal is to identify who is at risk and improve prevention and treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better ways to predict and prevent pulmonary hypertension crisis, potentially saving lives.
- What could go wrong
- This is an observational study, not a treatment trial. It may not directly lead to new therapies, and results might not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with pulmonary hypertension confirmed by right heart catheterization
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Pulmonary hypertension confirmed by mean pulmonary arterial pressure (mPAP) over 20 mmHg measured by right heart catheter * At least once per year of follow-up data collection record Exclusion Criteria: * Patients with missing baseline or follow-up data * Complicated by other diseases with significant influence on survival, such as acute coronary syndrome, malignancy, etc. * Complicated by other diseases with significant influence on hemodynamics, such as sepsis, acute left heart failure, and acute pulmonary embolism, etc. * Receiving medications with significant influence on hemodynamics
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Guangdong Province People's Hospital
RECRUITINGGuangzhou, Guangdong, China
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Peking Union Medical College Hospital
RECRUITINGBeijing, 100730, China
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Shanghai Pulmonary Hospital
RECRUITINGShanghai, China
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Yan'an Affiliated Hospital of Kunming Medical University
RECRUITINGKunming, Yunnan, China
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Other studies related to the condition(s) this trial covers.
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- Could a breath of oxygen during dialysis ease a hidden heart risk?
- Can GLP-1 drugs improve heart function during exercise in Obesity-Related heart failure?