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New combo therapy aims to wipe out rectal cancer before surgery

NCT ID NCT06770270

First seen Sep 30, 2025 · Last updated May 20, 2026 · Updated 34 times

Summary

This study tests whether adding the immunotherapy drug pucotenlimab to standard chemoradiation can help more people with locally advanced rectal cancer achieve a complete response before surgery. About 68 adults aged 18-75 will receive the combination, and researchers will check if the tumor disappears or shrinks enough for successful removal. The goal is to reduce the chance of cancer coming back.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Second Affiliated Hospital Of Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310009, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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