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Could a neck injection boost talk therapy for PTSD?

NCT ID NCT06570213

First seen Nov 24, 2025 · Last updated Jun 08, 2026 · Updated 19 times

Summary

This study tests whether adding a nerve block injection (stellate ganglion block) to standard talk therapy (cognitive processing therapy) helps reduce PTSD symptoms more than either treatment alone. About 270 adults with PTSD will be assigned to one of three groups: combination therapy, talk therapy plus a placebo injection, or the nerve block alone. The goal is to see which approach works best for short- and long-term symptom relief.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Rush University Medical Center

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.