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Mind over back pain? new study explores psychological predictors of recovery

NCT ID NCT07306312

Knowledge-focused Sponsor: University of Thessaly Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study investigates whether psychological factors like fear of movement, self-confidence, and mood can predict how much pain and disability improve after manual therapy in people with chronic low back pain. Sixty adults aged 18-65 with pain lasting over 3 months will be split into two groups: one receiving manual therapy alone, and the other adding Pain Neuroscience Education. The goal is to understand which psychological traits might help tailor future treatments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help therapists personalize treatment for chronic low back pain by identifying which psychological factors predict better outcomes.
What could go wrong
This is a small, early-stage observational study with only 60 participants, so results may not apply to everyone. It does not test a new treatment, only explores predictors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants should be between 18 and 65 years of age, * the pain in the lumbar region should last for more than 3 months, with at least one attack per week, * they should not have undergone physiotherapy in the last 6 months prior to the intervention * have a good knowledge of the Greek language and an adequate level of knowledge, to be informed and sign the consent form and questionnaires Exclusion Criteria: * people with clinical conditions that are contraindicated for physiotherapy, * patients who report red flags, * people with a history of lumbar surgery, * people with diagnosed neuromuscular diseases that significantly impair movement, * people with cardiovascular and respiratory diseases that cause severe shortness of breath or angina * people with mental disorders, as long as they hinder communication and cooperation with the researcher.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression Kinesiophobia Low Back Pain Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Disability physical Low back pain Manual theapy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Athens Scoliosis

    Athens, Greece

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