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New hope for rare blood cancers: first human trial of PRT12396 begins

NCT ID NCT07469891

First seen Mar 20, 2026 · Last updated May 20, 2026 · Updated 8 times

Summary

This early-stage study tests a new drug called PRT12396 in about 100 people with two rare blood cancers: polycythemia vera and myelofibrosis. The main goals are to find a safe dose and see if the drug can help control the disease. Participants must have a specific genetic mutation (JAK2 V617F) and be well enough for daily activities.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BRCR Global - Coral Springs

    RECRUITING

    Coral Springs, Florida, 33065, United States

  • START Midwest, LLC

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

Conditions

Explore the condition pages connected to this study.