Blood protein levels may predict stroke outcomes
NCT ID NCT07513428
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 79 people who had a stroke to see if levels of a protein called PrPC in their blood were linked to how severe the stroke was and how well they recovered. Researchers collected blood samples and checked patients' health 3 months later. No treatments were tested—the goal was simply to learn more about the role of this protein in stroke.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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79 people
The number who actually took part.
- Started
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Jun 2023
- Finished
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Sep 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
patients with anterior circulation ischemic stroke who were admitted to the Department of Neurology of the First Hospital of Jilin University within 48 hours of symptom onset and were aged 18-80 years were consecutively enrolled in this study. For wake-up strokes, onset was defined as last known well. Anterior circulation ischemic stroke patients were defined by infarct location within the ICA-MCA and/or ACA territories on MRI-DWI (supported by CTA/MRA when available).
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patients with anterior circulation ischemic stroke who were admitted to the Department of Neurology of the First Hospital of Jilin University within 48 hours of symptom onset and were aged 18-80 years Exclusion Criteria: * (1) patients who received intravenous thrombolysis or endovascular intervention; (2) patients with infectious diseases, autoimmune diseases, or those receiving immunosuppressive or immunomodulatory therapy; (3) patients with a history of cerebral infarction or intracerebral hemorrhage within the past year; (4) patients with severe hepatic or renal dysfunction, defined as alanine aminotransferase (ALT) or aspartate aminotransferase (AST) levels exceeding three times the upper limit of normal, serum creatinine levels \>265 μmol/L, heart failure, or malignant tumors.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The First Hospital of Jilin University
Changchun, Jilin, 130021, China