Could a blood injection heal damaged vocal cords?
NCT ID NCT07350642
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether injecting platelet-rich plasma (PRP) into the vocal cords can help people with vocal fold sulcus, scar, or atrophy. Researchers will measure voice quality and patient well-being in 48 participants over a follow-up period. The procedure is done under local anesthesia using a thin scope through the nose.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- platelet-rich plasma (PRP)
- What this could lead to
- If it works, this could offer a simple injection-based treatment to improve voice quality and daily life for people with certain vocal cord problems.
- What could go wrong
- This is a small, early-stage study with no control group, so results may not be conclusive. Risks include infection, bleeding, or no voice improvement.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 48 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Dec 2025
An estimate. Start dates often move.
- Expected to finish
-
Dec 2029
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
10 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 1-Age ≥ 10 years 2-Gender: both sexes will be included in the study 3-clinical diagnosis of vocal fold sulcus, scar or atrophy. 4-Diagnosis confirmed by video laryngoscope examination. 5-be able to participate and sign informed consent. Exclusion Criteria: 1- Laryngeal cancer. 2. Acute laryngeal infection . 3. Systemic diseases that may impair healing, such as:(Uncontrolled diabetes mellitus-Autoimmune disorders affecting the larynx-Coagulopathy or bleeding disorders). 4\. Use of systemic corticosteroids or immunosuppressive drugs within the last 4 weeks. 5\. Previous laryngeal surgery within the last 6 months 6. Pregnancy or lactation. 7. Known allergy or hypersensitivity to local anesthetics or any component used in PRP preparation. 8\. Inability to complete with follow-up visits or voice assessment protocols
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Vocal fold sulcus ,scar and atrophy are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
2 sites. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Assiut university
Asyut, Egypt
-
Faculty of medicine
Asyut, Egypt